If you are:

Aged ≥50-64 (with a known uderlying health condition such as weakened immune system (e.g. chemotherapy); heart disease and/ or hypertension; asthma or lung disease; diabetes not treated with insulin; mild hepatic impairment; stroke or neurological problem)

Or

Aged ≥65 (with or without comorbidity)

And you develop or have signs of COVID-19/Coronavirus infection symptoms in the last 14 days then you may be eligible to take part in the PRINCIPLE research trial

The PRINCIPLE trial tests different medicine treatments for COVID-19, further info at https://www.phctrials.ox.ac.uk/principle-trial.

This patient information leaflet explains what the study involves in detail.

Currently the PRINCIPLE trial is run via North Cumbria Integrated Care in the GP practices listed below.
If you have COVID19/coronavirus symptoms and wish to take part, please click on the relevant link next to the GP practice that you are registered with.

At present, those patients registered with the listed GP practices can participate via this website.

Other GP practices in Cumbria may be taking part, but please check with your own GP practice.

For more information specifically about the PRINCIPLE trial please phone 0800 138 0880 or email principle@phc.ox.ac.uk  

If you have health needs, then please contact your regular GP practice or 111.

Other clinical trials do not involve drugs or treatments. They may look at the care you receive and could also involve:

  • interviews
  • questionnaires
  • researchers studying how your care team communicates with you
  • taking a blood or tissue sample
  • participating as a healthy volunteer

All research studies are reviewed and approved by professional bodies before they begin. This includes a review by an independent Research Ethics Committee. Read more about how research is approved. 
 

Why take part in a clinical trial?

Clinical trials help doctors understand how to treat a particular illness. It may benefit you, or others like you, in the future. If you take part in a clinical trial, you may be one of the first people to benefit from a new treatment.
 

Do clinical trials have side effects?

If you’re trying a new type of treatment you may experience unknown side effects. We use this information to write the leaflets you find in boxes of medication, if the treatment goes on sale.
 

How do I take part in a clinical trial?

We’re always looking for volunteers to participate in our research studies. If you’re interested in becoming involved you can:

You may have agreed to be contacted about taking part in research studies when registered as a patient. If you agreed to this, members of our research teams may look at your medical records to see if you are eligible to take part in new research studies. You can ask for this to be stopped at any time by emailing research@ncic.nhs.uk

Befoe you take part in a study you’ll be given all the information about what it means for you. You’ll have plenty of time to ask questions and think about whether or not you want to take part. You will not be forced to take part in a study. You can ask to stop being part of a study at any time and your care will not be affected if you do.